Reading in cooler format files (.mcool/.scool) and aggregate plots for telomeres and centromeres

[Brahmandam-Gayatri]

Hello,

Thank you for mariner package in R. I have my Hi-C data for yeast in the format of cooler files and I was wondering how to load and use them with mariner. In addition, I want to plot aggregate plots as shown in the mariner workshop (https://ericscottdavis.com/Bioc2023mariner/articles/Bioc2023mariner.html) for telomeres and centromeres. I was able to plot for centromeres using other tools in python, but unable to do the same for telomeres. Any help in this regard is highly appreciated.

Thanks again!!
Gayatri.