mesoSPIM Control

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mesoSPIM-control is the open-source Python/PyQt acquisition software for mesoSPIM light-sheet microscopes. It drives all hardware, manages acquisition protocols, and provides a GUI for multichannel, multiview, and tiled imaging of large cleared-tissue samples.

Tip

New to mesoSPIM? Start with the Getting Started page to install the software and run it in demo mode within minutes.

Note

These docs were initially drafted with AI assistance and may contain inaccuracies or gaps. If you spot an error or something unclear, please open an issue on GitHub or post in the image.sc forum — your feedback is very welcome!


Getting Started

Quick-start guide — clone, install, and launch in demo mode.

Getting Started
Installation

Full installation instructions, including device drivers.

Installation
Configuration

How to write and manage your hardware configuration file.

Configuration
User Guide

Walk-through of the GUI, acquisition modes, and scripting.

User Guide
Supported Hardware

Cameras, stages, filter wheels, lasers, and more.

Supported Hardware
Changelog

Release notes and version history.

Changelog

Indices and tables