thinkCADASIL
A group dedicated to raising CADASIL awareness in local & medical communities.
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thinkCADASIL is a group of CADASIL patients, their family, and friends dedicated to raising CADASIL awareness and funds for research. CADASIL is a rare genetic blood disorder caused by a mutation on the Notch 3 gene. The mutation leads to a misfolding of protein in the smooth muscle walls of small and medium blood vessels. Over time, the blood vessels weaken, causing them to collapse or weep. Although systemic, brain tissue is primarily impacted by this protein misfolding. Progression of CADASIL can lead to migraines, strokes, tremors, mood disorders, cognitive decline, and dementia. Severity of symptoms differs between individuals. It is often misdiagnosed as common neurodegenerative diseases, such as MS, ALS, or Alzheimer's. It is believed 1 in 450 people carry a Notch 3 mutation. Thank you for watching our channel and educating yourself about CADASIL. Check back regularly for more content or go to www.thinkCADASIL.org. Working together will lead to treatments and a cure.
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