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NanoKnee operates regenerative orthopedic medicine clinics across seven locations in the United States and Mexico, providing both surgical and non-surgical treatments for knee conditions. The practice maintains facilities in Fort Lauderdale, Houston, Phoenix, Miami, San Jose, Beverly Hills, and Tijuana. Their clinical focus encompasses osteoarthritis, meniscal tears, and ligament damage repair. The medical team delivers four primary regenerative treatment modalities: Platelet-Rich Plasma therapy, mesenchymal stem cell procedures, prolotherapy, and amniotic allograft transplantation. These biologics-based interventions complement traditional orthopedic surgeries including total knee arthroplasty. Each facility houses specialized equipment for regenerative medicine procedures. NanoKnee's orthopedic surgeons specialize in addressing chronic knee pain through combined therapeutic approaches targeting underlying joint pathology. The practice documents surgical outcomes and maintains clinical data on regenerative treatment efficacy. Their facilities serve patients seeking alternatives to conventional knee replacement surgery.