Argajit Sarkar

I am a Second-year PhD candidate in the Department of Molecular Biology and Bioinformatics at Tripura University, under the guidance of Dr. Surajit Bhattacharjee, Associate Professor and Head of Department.

My research is dedicated to tackling the critical threat of Antimicrobial resistance, synergizing computational and experimental methods, utilizing In-vitro Experiments, Machine learning, and Large Language Models (LLMs) to predict novel antimicrobial candidates and frameworks.

Before this, I had worked at the Laboratory of Molecular Biology and Bioinformatics, where we explored the Combinatorial Antimicrobial and Anti-Virulence Potential of Quercetin with Antibiotics Against Vibrio cholerae. I received my B.Sc in Human Physiology (Sept, 2022) at Holy Cross College, Tripura, India. At Tripura University (Central University), I got an M.Sc in Molecular Biology & Bioinformatics (June, 2024). Apart from that, I'm also an NEP 2020 Ambassador, promoting key policies and initiatives of the University Grants Commission (UGC) and Ministry of Education (Govt. of India).

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RESEARCH/ REVIEW/ BOOK-CHAPTER/ PRE-PRINTS

Quercetin Research paper thumbnail

Quercetin as an additive adjuvant enhances ciprofloxacin and tetracycline efficacy against Vibrio cholerae by disrupting membranes, inhibiting biofilms, and reducing virulence levels

Suman Paul, Argajit Sarkar, Manisha Ghosh, Debajyoti Datta, Moumita Debnath, Surajit Basak, Saumya Raychaudhuri, Surajit Bhattacharjee

3 Biotech, December 1, 2025

View Paper / Cited by 0

Quercetin (QR), a plant-derived flavonoid, was evaluated as an adjuvant to enhance ciprofloxacin (CP) and tetracycline (TE) efficacy against Vibrio cholerae O1 El Tor (C6706) and non-O1/non-O139 (SC134) strains. Checkerboard assays revealed additive effects (FICI = 0.75) for QR+CP and QR+TE against both strains, with synergy (FICI = 0.5) for QR+TE in C6706.

Biofilm-mediated bioremediation paper thumbnail

Biofilm-mediated bioremediation of xenobiotics and heavy metals: a comprehensive review of microbial ecology, molecular mechanisms, and emerging biotechnological applications

Argajit Sarkar, Surajit Bhattacharjee

3 Biotech, March 7, 2025

View Paper / Cited by 13

This comprehensive review explores the potential of bacterial biofilms in bioremediation, focusing on their ability to degrade and transform a wide array of pollutants, including heavy metals, persistent organic pollutants (POPs), oil spills, pesticides, and emerging contaminants, such as pharmaceuticals and microplastics. [3, 9]

TGF-beta paper thumbnail

TGF-beta plays dual roles in immunity and pathogenesis in leishmaniasis

Susmita Barik, Sanghamitra Goswami, Prakash Kumar Nanda, Argajit Sarkar, Bhaskar Saha, Arup Sarkar, Surajit Bhattacharjee

Cytokine, January 27, 2025

View Paper / Cited by 8

Transforming growth factor-beta (TGF-β), displaying a dual role in immunosuppression and pathogenesis, has emerged as a key regulator of anti-leishmanial immune responses. [2] In Leishmania infections, TGF-β drives immune deviation by enhancing regulatory T-cell (T-reg) differentiation and inhibiting macrophage activation, suppressing critical antiparasitic responses.

Periodontis paper thumbnail

Harnessing Generative Artificial Intelligence for Periodontitis Prediction: A Machine Learning Approach Integrating Systemic Health Indicators for Precision Oral Health in Resource-Limited Settings

Argajit Sarkar, Espita Ghosh, Surajit Bhattacharjee

SSRN Preprint, July 5, 2025

View Paper / Cited by 0

Periodontitis affects over 11% of the global population, with severe cases projected to reach 1.5 billion by 2050. In India, 19% of adults suffer from severe periodontitis. This study explores the novel application of Generative Artificial Intelligence (GenAI), specifically ChatGPT-4o, to enhance periodontitis prediction by linking systemic health indicators to oral disease progression. [7]

LICENSES/ CERTIFICATIONS/ AWARDS

National & International Conference

  • Research Symposium on Artificial Intelligence and Computational Biology (AICBio 25) - Awarded Third Place for Poster"
    December 3rd - 5th, 2025
    AICBio 25, the Research Symposium on Artificial Intelligence and Computational Biology, was held from December 3rd to 5th, 2025, at the School of Artificial Intelligence, Amrita Vishwa Vidyapeetham, Coimbatore, Tamil Nadu, India
    ACBIO third place certifiate
    View original certificate (PDF)
  • Presented Poster at 11th India International Science Festival (IISF) 2025, Panchkula, Haryana, India "
    December 6th - 9th, 2025
    Jointly organized DST, Govt. of India, the DBT, Govt. of India, the DOS, Govt. of India, and DAE
    IISF certifiate
    View original certificate (PDF)
  • Presented Poster at International Conference on Advances in Biotechnology, Bioprocessing and Structural Biology (ICABSB-2025) at ITT Roorkee, "
    December 11th - 14th, 2025
    Jointly organized by the Indian Institute of Technology Roorkee (IITR) and The Biotech Research Society, India (BRSI), and held at Roorkee, India
    ICABSB certifiate
    View original certificate (PDF)

Data Science & Analytics

    Python for Data Science and Artificial Intelligence"
    IBM, Issued May 2025
    Relevant Skills: Python, Data Science
    American Society for Microbiology Membership
    View original certificate (PDF)
  • Data Analysis with ChatGPT
    365 Data Science, Issued November 2024
    Credential ID: CC-FB6B33CB37
    Relevant Skills: Data Analysis, Statistical Data Analysis
  • Introduction to Data and Data Science
    365 Data Science, Issued November 2024
    Credential ID: CC-70B1CBF9A3
  • Understanding Data Visualization
    DataCamp, Issued November 2024
    Credential ID: d860df08f4b1b2114d0072fc55ca03f3932b962a

Machine Learning & AI

  • Certificate of completion - AI Ethics
    365 Data Science, Issued April 2025
    Credential ID: 1a8a1e9e4a
  • NPTEL+ Workshop: WEKA Machine Learning for Healthcare
    NPTEL, Issued February 2025
    Credential ID: NP25WS227620603284 (View Certificate (PDF))
    Relevant Skills: Machine Tools, Machine Learning, Bioinformatics, Weka
  • ChatGPT and Generative AI
    365 Data Science, Issued November 2024
    Credential ID: CC-3D92AF4DD9
  • Understanding Machine Learning
    DataCamp, Issued November 2024
    Credential ID: 736828043119ec438e22a229c26f0ca64ebea1fd
  • Foundational Artificial Intelligence course by Skillup Online
    Nasscom Foundation, Issued October 2020
    (View Certificate (PDF))

Bioinformatics & Genomics

  • Genomic Data Science
    Coursera, Issued April 2025
    (View Certificate (PDF) Credential: Coursera 0Q8CTG38Q19J)
  • Workshop on "Multi-Ligand Docking Training with Vina and PyRx!"
    Research Boulevard, Issued October 2024
    Credential ID: RBT/MD/ADMET/14/10/24/0054 (View Certificate (PDF))
    Relevant Skills: Molecular docking, Drug Discovery, Autodock Vina
  • 2 Day Hands-on workshop "Comparative Genomics: Evolutionary Genomics Application"
    Kent State University, Issued May 2024
    Relevant Skills: Bioinformatics, Evolution, Evolutionary Biology
    Kent State Comparative Genomics Workshop Certificate
    View original certificate (PDF)

Other Relevant Certifications & Workshops

  • IIT KANPUR 12 Weeks course: Wildlife Ecology
    NPTEL, Issued January 2024
    (View Certificate (PDF))
    Relevant Skills: Ecology, Wildlife Biology

Professional Affiliations

    ASM Global Outreach-Student Member"
    American Society for Microbiology, Issued January 2025
    Relevant Skills: Bioinformatics, Evolution, Evolutionary Biology
    American Society for Microbiology Membership
    View original certificate (PDF)

    Awards and Honors

    • Participated as Delegate at India International Science Festival (IISF)-2024
      Organised at IIT Guwahati, Assam, India
      India International Science Festival 2024
      View original certificate (PDF)
      • Oral Presentation at NCRTBSNEI-2025
        Tripura University (National Conference), Issued 28th March, 2025
        National Conference at Tripura University
        View Award Certificate (PDF)
      • Santanu Kar Memorial Merit Award
        Holy Cross College, Agartala, Issued February 2021
        Awarded for academic excellence during the academic year 2019/2020.
        View Award Certificate (PDF)